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The challenge of detecting NTRK fusions across tumour types

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Published: 21.10.19
Views: 896

Professor Dr Marc Peeters, Professor Caterina Marchio

NTRK fusions are an actionable molecular target that occur in ~1.0% of all cancers, although this varies greatly across specific tumour types. Where an NTRK fusion is identified, it can be treated with a TRK inhibitor - regardless of the tumour histology or prior treatment lines. But how can we identify such rare mutations?

To help guide clinicians in implementing routine NTRK screening, the ESMO Translational Research and Precision Medicine Working Group have developed a consensus statement on suitable testing approaches, including a simple algorithm.

Join lead author Professor Caterina Marchiò and our chair, Professor Dr Marc Peeters, for an in-depth discussion of TRK fusion cancer.

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This independent educational activity is supported by an educational grant from Bayer Pharmaceuticals. The educational content has been developed by Liberum IME and validated by an independent steering committee; Bayer Pharmaceuticals have had no influence on the content of this education.

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